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Deciding Which Infusion Pump to Use
Deciding between the ALZET® Osmotic Pump and iPRECIO® Programmable Infusion Pump for your study does not have to be a grueling process. Below we’ve highlighted the benefits of each pump and summarized their similarities and differences to help you make your decision. As always, if you’re still stuck, don’t hesitate to contact ALZET Technical Support for more guidance.
Small, implantable pumps for research in mice, rats, and other laboratory animals.
The unique mechanism by which ALZET pumps operate, allows compounds of any molecular conformation to be delivered predictably at controlled rates, independent of their physical and chemical properties.
These minipumps deliver drugs, hormones, and other test agents at continuous and controlled rates, for durations ranging from one day to six weeks, without the need for external connections or frequent handling. Their unattended operation eliminates the need for repeated nighttime or weekend dosing by lab personnel.
ALZET minipumps can be used for systemic administration when implanted subcutaneously or intraperitoneally. They can also be attached to a catheter for intravenous, intracerebral, intra-arterial infusion, or targeted delivery.
An advanced infusion device for drug delivery applications in mice, rats and larger animals.
With versatile, programmable functions and a refillable reservoir, this implantable infusion pump enables full control over dosing studies and empowers researchers to execute even the most complex dosing protocols. These include: multiple bolus dosing, variable/constant delivery, escalating drug administration, and more.
With the user-friendly iPRECIO management software, the infusion profile is programmed and downloaded to the pump’s memory chip. Pump refilling is possible via a percutaneously accessible septum, enabling researchers to change solutions or refill the pump during the course of the study.
ALZET® Osmotic Pumps
Small, implantable pumps for research in mice, rats, and other laboratory animals.
The unique mechanism by which ALZET pumps operate, allows compounds of any molecular conformation to be delivered predictably at controlled rates, independent of their physical and chemical properties.
These minipumps deliver drugs, hormones, and other test agents at continuous and controlled rates, for durations ranging from one day to six weeks, without the need for external connections or frequent handling. Their unattended operation eliminates the need for repeated nighttime or weekend dosing by lab personnel.
ALZET minipumps can be used for systemic administration when implanted subcutaneously or intraperitoneally. They can also be attached to a catheter for intravenous, intracerebral, intra-arterial infusion, or targeted delivery.
iPRECIO® Programmable Pumps
An advanced infusion device for drug delivery applications in mice, rats and larger animals.
With versatile, programmable functions and a refillable reservoir, this implantable infusion pump enables full control over dosing studies and empowers researchers to execute even the most complex dosing protocols. These include: multiple bolus dosing, variable/constant delivery, escalating drug administration, and more.
With the user-friendly iPRECIO management software, the infusion profile is programmed and downloaded to the pump’s memory chip. Pump refilling is possible via a percutaneously accessible septum, enabling researchers to change solutions or refill the pump during the course of the study.
Summary
The table below reviews the similarities and differences between the pumps.
ALZET Osmotic Pumps
iPRECIO Programmable Pumps
Operation Method
Osmotic
Peristaltic
Implantable
Yes
Yes
Programmable
No
Yes
Infusion Modes
Continuous
(Delayed and Circadian w/Catheter)
(Delayed and Circadian w/Catheter)
Continuous, Variable
Intermittent, Circadian, Delayed
Intermittent, Circadian, Delayed
Infusion Rates
Fixed
0.08 – 10 μl/hr
0.08 – 10 μl/hr
Programmable
SMP-200: 0.1–30 μl/hr
SMP-310R: 0.1 – 10 μl/hr
SMP-200: 0.1–30 μl/hr
SMP-310R: 0.1 – 10 μl/hr
Reservoir Volumes
100 μl
200 μl
2 ml
200 μl
2 ml
SMP-200: 900 μl
SMP-310R: 130 μl
SMP-310R: 130 μl
Durations
Fixed*
1 day, 3 days, 1 week, 2 weeks, 4 weeks, 6 weeks
1 day, 3 days, 1 week, 2 weeks, 4 weeks, 6 weeks
Programmable †
SMP-200: up to 6 months
MP-310R: up to 67 days
SMP-200: up to 6 months
MP-310R: up to 67 days
Size
100 μl: 1.5 x 0.6 cm
200 μl: 3.0 x 0.7 cm
2 ml: 5.1 x 1.4 cm
200 μl: 3.0 x 0.7 cm
2 ml: 5.1 x 1.4 cm
SMP-200: 3.87 x 1.92 x 0.97 cm
SMP-310R: 2.48 x 1.50 x 0.82 cm
SMP-310R: 2.48 x 1.50 x 0.82 cm
Empty Weight
100 µl: 0.4 g
200 µl: 1.1g
2 ml: 5.1 g
200 µl: 1.1g
2 ml: 5.1 g
SMP-200: 7.9g
SMP-310R: 3.4 g
SMP-310R: 3.4 g
Accuracy
> +/- 10%
> +/- 5%
Type of Use
Single use; disposable
Single use; disposable
Animal Species
100 μl and 200 μl: Mice and larger
All pumps: Rats and larger
All pumps: Rats and larger
SMP-200: Rats and larger
SMP-310R: Mice and larger
SMP-310R: Mice and larger
Battery Life ‡
N/A
SMP-200: 7 days – 6 months
SMP-310R: 5 days – 67 days
SMP-310R: 5 days – 67 days
Design
Simple Design
No moving parts, no batteries, no electronics
No moving parts, no batteries, no electronics
Advanced Design
Electronics and moving parts
Electronics and moving parts
Research Use
Over 45 years
Over 23,000 publications
Over 23,000 publications
Over 15 years
Over 1500 publications
Over 1500 publications
Cost
Cost-effective
Higher budget studies
*Longer duration possible with pump replacements
†Depending on flow rate and battery life>
‡Depending on flow rate and, for SMP310R, communication level