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Isoflurane Anaesthesia System, U-410
The Univentor 410 Anaesthesia unit is a complete unit for Isoflurane anaesthesia for animals weighing from 15gr up to 500gr. It has a built-in flow meter for air and vaporizer calibrated for Isoflurane.
The airflow as well as the isoflurane concentration are constantly shown on the display. Isoflurane is filled in a 10 ml gastight syringe and is dosed with exact precision into a small vaporizer where it is mixed and led to a chamber, mask or ventilator. Due to the special vaporizer the airflow is much lower than traditional units. Typical maintenance dose for mice is 2,2% Isoflurane and 200 ml/min air. With these settings only 1,2 ml Isoflurane is used per hour. This gives you essential savings of Isoflurane (approx. 70%).
When the U-410 is in operation the % anaesthetic value and the airflow are constantly shown on the LED display (air 200 ml/min-Isoflurane 2,2%). Both parameters can be continuously changed during operation.
The U-410 has a built-in alarm if airflow or anaesthesia is blocked. The apparatus provides a very small footprint and measures 23 x 13 x10 cm. Weight 1,8 kg
Featured in Research
Gian Pietro Serra, François Georges, Åsa Wallén-Mackenzie, Opto-Avoidance-Elevated Plus Maze protocol to study positive or negative valence upon optogenetic stimulation in the mouse brain, STAR Protocols, Volume 5, Issue 4, 2024, 103474, ISSN 2666-1667, https://doi.org/10.1016/j.xpro.2024.103474
Nilsson, J., Holmberg, D., Schmidt-Christensen, A. Longitudinal In Vivo Imaging and Quantification of Human Pancreatic Islet Grafting and Contributing Host Cells in the Anterior Eye Chamber. J. Vis. Exp. (160), e61234, https://doi.org/10.3791/61234 (2020).
Linnell, John & Gorini, Lucrezia & Wedul, Sari Jemiina & Arnemo, Jon & Boitani, Luigi & Nilsen, Erlend. (2013). Field anesthesia of least weasels (Mustela nivalis nivalis) with isoflurane. Wildlife Biology in Practice. 9. 7-13. https://doi.org/10.2461/wbp.2013.9.2
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